AMA #12: Thoughts on Longevity Supplements (Resveratrol, NR, NMN, Etc.) & How to Improve Memory

About this video

In this AMA, Huberman gives his assessment of longevity supplements including resveratrol, NR, and NMN, and also addresses how to improve memory. On resveratrol, Huberman argues that by 2023 the claim that it extends lifespan has largely been debunked, saying there is very little if any direct evidence for lifespan extension, though it may have other cellular effects. He notes he personally takes grape seed extract, which he describes taking mainly for vascular function and blood flow rather than longevity. Huberman also discusses raising NAD directly, describing his own experience with NAD infusions, which he found pretty uncomfortable during administration but says left him feeling much better afterward, while emphasizing that he is aware of no clinical trial of NAD infusion for vigor and that safety decisions belong with a physician.

Key takeaways

  • Huberman argues resveratrol has very little if any direct evidence for extending lifespan.
  • Huberman says he takes grape seed extract mainly for vascular function and blood flow, not longevity.
  • Huberman describes NAD infusions as uncomfortable during administration, based on his own experience.
  • Huberman emphasizes there is no clinical trial he knows of testing NAD infusion for vigor.
  • Huberman advises exploring whether such interventions are safe for you with your physician.

Episode details: published October 31, 2023 · 321K views · 29:08 long. Summary written by Self Growth Videos from the episode itself. The science and protocols described are Andrew Huberman’s, presented for education — not medical advice. Consult a qualified professional before changing your own health practices.


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