How to Optimize Female Hormone Health for Vitality & Longevity | Dr. Sara Gottfried

About this video

Dr. Sara Gottfried, an obstetrician-gynecologist and clinical professor, joins Huberman to discuss female hormone health across puberty, young adulthood, adulthood, perimenopause and menopause, combining traditional medicine with nutrition, supplementation and behavioural practices. She discusses the gut microbiome and how, she explains, it influences estrogen metabolism, testosterone, thyroid and growth hormone, as well as omega-3 fatty acids and the balance of resistance to cardiovascular training for women. Huberman notes Dr. Gottfried points out women experience digestive issues far more frequently than men. In the middle excerpt she argues opportunities differ by decade: knowing about high androgens in the teenage years, or high cortisol in the twenties, could change how a woman cares for herself, and she describes testosterone declining with age and stress.

Key takeaways

  • Dr. Gottfried discusses hormone health across every stage from puberty to menopause.
  • Dr. Gottfried explains the gut microbiome influences estrogen, testosterone, thyroid and growth hormone.
  • Dr. Gottfried highlights omega-3 fatty acids as particularly important for female hormone health.
  • Dr. Gottfried argues health opportunities and priorities differ by decade.
  • Huberman notes Dr. Gottfried’s point that digestive issues are far more frequent in women.

Episode details: published January 30, 2023 · 2.3M views · 2:35:05 long. Summary written by Self Growth Videos from the episode itself. The science and protocols described are Andrew Huberman’s, presented for education — not medical advice. Consult a qualified professional before changing your own health practices.


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