Tools for Hormone Optimization in Males | Dr. Kyle Gillett

About this video

Dr. Kyle Gillett, a dual board-certified physician in family and obesity medicine, joins Huberman to discuss male hormone optimisation across adolescence, adulthood and older age. They cover behavioural foundations, nutrition, supplements and prescription tools, and their interactions in shaping testosterone, free testosterone, dihydrotestosterone, estrogen, growth hormone, thyroid hormone and other hormones affecting mood, libido, strength and cognition. Dr. Gillett offers specific guidance on how to judge whether testosterone is optimised, how often to test, and how to calibrate subjective measures such as libido, plus whether to cycle interventions. In the middle excerpt they discuss DHT, beard growth and hair loss, with Dr. Gillett explaining receptor sensitivity is genetically determined and the androgen receptor gene sits on the X chromosome, and they review supplements including creatine and betaine.

Key takeaways

  • Dr. Gillett discusses testosterone, DHT, estrogen, growth hormone and thyroid hormone as an interacting system.
  • Dr. Gillett offers guidance on testing frequency and judging whether hormones are optimised.
  • Dr. Gillett explains DHT effects on facial and scalp hair depend on genetically determined receptors.
  • Dr. Gillett discusses creatine and betaine among supplement tools for men.
  • Huberman frames behavioural foundations as the base of hormone optimisation at every age.

Episode details: published December 12, 2022 · 1.2M views · 2:24:18 long. Summary written by Self Growth Videos from the episode itself. The science and protocols described are Andrew Huberman’s, presented for education — not medical advice. Consult a qualified professional before changing your own health practices.


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