Using Cortisol & Adrenaline to Boost Our Energy & Immune System Function

About this video

Huberman explains how cortisol and adrenaline, also called epinephrine, can be used to boost energy and immune function. Huberman explains that the nervous system provides the alarm signal that liberates immune killer cells, and that while stress held too high for too long can hinder the immune response, for a period of about one to four days stress can actually protect by increasing the immune response. He says this effect is governed by epinephrine released from the adrenals, noting that in his account the effect disappears when the adrenals are removed. Huberman therefore argues that short bouts of very intense exercise, probably no more than an hour per day, cold water exposure, or cyclical breathing can bolster the immune system by raising epinephrine, provided sleep and nutrition are in place. He extends the same logic to caffeine, arguing its immune effects likely depend on whether it is used to spike adrenaline occasionally rather than consumed chronically, and he suggests using such adrenaline-raising behaviors two or three times a week at minimum for people frequently exposed to illness.

Key takeaways

  • Huberman explains that short-term stress of about one to four days can enhance immune response in his account.
  • Huberman attributes the immune effect to epinephrine released from the adrenal glands.
  • Huberman recommends short intense exercise, cold exposure, or cyclical breathing to raise epinephrine.
  • Huberman argues that caffeine’s immune effects depend on occasional spiking versus chronic use.
  • Huberman stresses that these tools assume sleep and nutrition are already handled.

Episode details: published May 3, 2021 · 663.4K views · 1:46:38 long. Summary written by Self Growth Videos from the episode itself. The science and protocols described are Andrew Huberman’s, presented for education — not medical advice. Consult a qualified professional before changing your own health practices.


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