Dr. Will Cole: Insulin Resistance Is Fueling Your Cellular Aging | TUH #308

About this video

Brecka interviews functional-medicine practitioner Dr. Will Cole about cellular health and Cole’s new book with Dr. Josh Axe. Cole argues insulin resistance accelerates cellular aging — claiming, as presented, that millennials and Gen X are aging faster at the cellular level — and that gut permeability, toxin load, mitochondrial dysfunction and psychological stress make cells feel ‘unsafe’ and defensive. They discuss blood markers and DNA-methylation organ-age testing Cole uses to target which organs are aging fastest, and Cole closes on adding life to years, not just years to life. Note: the transcript provided is an Arabic-language dub.

Key takeaways

• Cole claims insulin resistance is a central accelerator of cellular aging, in his argument
• Cole argues cellular dysfunction underlies the gut, hormone and inflammation problems functional medicine treats
• He states organ-specific aging can now be estimated with methylation-based tests he uses clinically
• Cole argues purpose, relationships and enjoyment are the point of longevity work, in his view

Episode details: published September 29, 2026 · 29.6K views · 57:38 long. Summary written by Self Growth Videos from the episode itself. Gary Brecka is a commercial health figure, not a physician. The claims described are Brecka’s or his guests’, presented for education — not medical advice and not endorsed by Self Growth Videos. Consult a qualified professional before changing your own health practices.

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