How to Combine GLP-1s and Growth Hormone Peptides Safely with Dr Jason Pencek

About this video

Woodward interviews Dr. Jason Pensac, a practitioner who has used peptides clinically for over six years. Pensac describes his journey into peptide therapy, beginning with growth hormone peptides and eventually incorporating GLP-1 agonists, BPC-157, and other compounds into his practice. He emphasizes his clinical philosophy of starting patients on simple protocols—typically hormones first, then adding GLP-1s or growth hormone peptides—and building slowly over time to avoid overwhelm and identify what works for each individual.

Key takeaways

• Pensac argues that growth hormone peptides (such as CJC-1295, tesamorelin, and sermorelin) can improve energy, sleep, mood, muscle mass, and recovery, with tesamorelin claimed to be the strongest growth hormone releaser but also most likely to cause water retention and hunger.
• He claims testosterone is essential for women in perimenopause and menopause, asserting it improves energy, libido, muscle retention, and mood, and should be optimized alongside GLP-1 agonists to preserve muscle mass during weight loss.
• According to Pensac, GLP-1 agonists can be used long-term at low doses for metabolic and cardiovascular benefits beyond weight loss, including reduced inflammation and lower risk of heart disease, Alzheimer’s, and Parkinson’s, and he believes they are safe for extended use based on clinical experience and available data.

Episode details: published July 31, 2026 · 37 views · 58:30 long. Summary written by Self Growth Videos from the episode itself. The hormone and peptide concepts described are Jennifer Woodward’s, presented for education — not medical advice. Consult a qualified professional before changing your own health practices. Disclosure: Jennifer Woodward sells a Peptides for Practitioners certification.

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